Microbiology
Bacteria, viruses, immunology, genetics
31 Questions 10 Topics Take Test
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Which virus possesses a segmented genome and is responsible for causing influenza pandemics?
A Influenza A virus
B Rotavirus
C Bunyavirus
D Arenavirus
Correct Answer:  A. Influenza A virus
EXPLANATION

Influenza A virus has 8 RNA segments, enabling antigenic reassortment. This segmentation allows rapid evolution and pandemic potential through genetic exchange with other influenza strains.

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Which bacterial genus produces endospores as a survival mechanism under nutrient-depleted conditions?
A Bacillus and Clostridium
B Staphylococcus and Streptococcus
C Vibrio and Campylobacter
D Salmonella and Shigella
Correct Answer:  A. Bacillus and Clostridium
EXPLANATION

Bacillus and Clostridium are the primary gram-positive bacteria capable of forming endospores. These structures are highly resistant to heat, chemicals, and radiation.

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Which of the following bacterial structures is responsible for horizontal gene transfer through direct cell-to-cell contact?
A Pili
B Flagella
C Capsule
D Teichoic acid
Correct Answer:  A. Pili
EXPLANATION

Pili (sex pili) mediate bacterial conjugation, enabling direct DNA transfer between cells. Flagella aid motility, capsules provide protection, and teichoic acids are cell wall components.

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Which statement correctly describes the difference between prokaryotic and eukaryotic cells?
A Prokaryotes have a nucleus; eukaryotes do not
B Prokaryotes lack a nucleus and membrane-bound organelles; eukaryotes have both
C Both have identical cell wall composition
D Eukaryotes are always smaller than prokaryotes
Correct Answer:  B. Prokaryotes lack a nucleus and membrane-bound organelles; eukaryotes have both
EXPLANATION

Prokaryotes (bacteria and archaea) lack a membrane-bound nucleus and organelles, with circular DNA. Eukaryotes (animals, plants, fungi) have a true nucleus and membrane-bound organelles with linear chromosomes.

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Which virus causes chickenpox and shingles?
A Varicella-zoster virus
B Cytomegalovirus
C Epstein-Barr virus
D Human papillomavirus
Correct Answer:  A. Varicella-zoster virus
EXPLANATION

Varicella-zoster virus (VZV) causes varicella (chickenpox) in primary infection. The virus remains dormant in nerve tissue and reactivates as herpes zoster (shingles) later in life.

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Which virus is a retrovirus and causes AIDS?
A Hepatitis B virus
B Human immunodeficiency virus (HIV)
C Herpes simplex virus
D Measles virus
Correct Answer:  B. Human immunodeficiency virus (HIV)
EXPLANATION

HIV is a retrovirus that carries reverse transcriptase enzyme to convert RNA to DNA. It causes acquired immunodeficiency syndrome (AIDS). Hepatitis B is a hepadnavirus, HSV is a herpesvirus.

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Which bacterial structure is responsible for motility in most bacteria?
A Pili
B Flagella
C Capsule
D Mesosomes
Correct Answer:  B. Flagella
EXPLANATION

Flagella are whip-like appendages that enable bacterial motility. Pili are used for attachment and DNA transfer, capsule provides protection, and mesosomes are infoldings of cell membrane.

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Which of the following bacteria causes tuberculosis in humans?
A Mycobacterium leprae
B Mycobacterium tuberculosis
C Corynebacterium diphtheriae
D Staphylococcus aureus
Correct Answer:  B. Mycobacterium tuberculosis
EXPLANATION

Mycobacterium tuberculosis is the causative agent of tuberculosis (TB). M. leprae causes leprosy, C. diphtheriae causes diphtheria, and S. aureus causes various infections.

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Which virus is responsible for causing COVID-19?
A SARS-CoV-1
B SARS-CoV-2
C MERS-CoV
D HCoV-OC43
Correct Answer:  B. SARS-CoV-2
EXPLANATION

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) is the virus responsible for the COVID-19 pandemic that emerged in late 2019. SARS-CoV-1 caused the 2003 outbreak.

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The cell wall of bacteria primarily contains which polysaccharide?
A Cellulose
B Peptidoglycan
C Glycogen
D Starch
Correct Answer:  B. Peptidoglycan
EXPLANATION

Peptidoglycan is the major structural component of bacterial cell walls, forming a rigid framework. It contains N-acetylglucosamine and N-acetylmuramic acid linked by peptide bridges.

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