Entrance Exams
Govt. Exams
Ureaplasma urealyticum is a cell wall-deficient bacterium that produces urease enzyme and characteristically forms small translucent 'fried egg' colonies on CCDC (Chocolate Casitone Dextrose Cholesterol) medium. It's a common cause of non-gonococcal urethritis and UTIs. While Proteus also produces urease, it doesn't form fried egg colonies and has a cell wall.
Actinobacteria, particularly Streptomyces species, form branching hyphae and mycelial networks resembling fungi, though they are prokaryotes producing many clinically useful antibiotics.
Poliovirus uses IRES sequences to initiate cap-independent translation, allowing ribosome binding internally and production of polyprotein without 5' capping.
Mycobacterial persistence involves multiple mechanisms: mycolic acid impedes drug entry, biofilm protects bacteria, and resistance mutations emerge under selective pressure.
Reverse transcriptase synthesizes DNA from viral RNA, enabling retroviruses like HIV to establish infection by converting their genome for integration into host DNA.
Staphylococcal enterotoxins function as superantigens, directly cross-linking MHC and TCR molecules, causing massive cytokine release and toxic shock syndrome.
All three viral pathogens have demonstrated zoonotic transmission capabilities with pandemic potential, requiring surveillance and monitoring by health authorities.
E. coli is a gram-negative bacterium with LPS in its outer membrane, which acts as an endotoxin triggering inflammatory responses in host infections.
Plasmids are extra-chromosomal DNA elements that carry multiple antibiotic resistance genes and can be horizontally transferred between bacteria, leading to multi-drug resistance.
A. baumannii survives on dry surfaces and spreads via contact; it is a major nosocomial pathogen in ICU settings.