Tamil Nadu has 38 districts as per the latest administrative reorganization, including districts created through subdivision of larger districts.

Though JN Port is in Mumbai, Chennai Port is the major port in Tamil Nadu. As of recent data, JN Port Mumbai remains the busiest, but Chennai Port is second largest in container traffic in South India.

Kongu Nadu, a historical region of the Chola and Pandya empires, corresponds to the present-day Coimbatore and Tiruppur districts in Western Tamil Nadu.

The Cauvery Waters Disputes Tribunal (CWDT) issued its final award in 1992, though the implementation and subsequent disputes continue with Supreme Court interventions as recent as 2018.

Sathyamangalam Tiger Reserve is located in Erode district and is one of Tamil Nadu's important tiger conservation areas, part of the Nilgiri Biosphere Reserve.

The Madras High Court was established in 1865 as one of the first high courts in India. It is the second oldest high court after the Calcutta High Court.

Though Jotirao Phule founded the Satyashodhak Samaj in Maharashtra, Periyar E.V. Ramasamy was a prominent Tamil Nadu-based social reformer who spearheaded similar reform movements in the state.

The Third Sangam was traditionally associated with Madurai according to Tamil literary tradition, though its historical accuracy is debated.

Adichanallur, an important Neolithic and early Iron Age site, is located in Thoothukudi district and has yielded significant archaeological findings.

Ramakrishna Mission Vivekananda College in Mylapore, Chennai, was established in 1891 as part of Ramakrishna Mission's educational initiatives.