Govt. Exams
Entrance Exams
Heteroduplex analysis uses electron microscopy to visualize DNA-RNA hybrids. Introns form loops that are clearly visible, confirming their presence.
Cry1Ac toxin from Bacillus thuringiensis specifically targets lepidopteran pests like cotton bollworms. It binds to specific receptors in their midgut.
MboI produces sticky ends identical to EcoRI due to recognition of similar DNA sequences (GATC), making them compatible for ligation.
The GEAC, functioning under the MOEFCC, is the apex body responsible for appraisal and approval of proposals relating to release of GMOs and products into the environment.
Mosaicism occurs when CRISPR editing is performed early in development, resulting in some cells being edited while others retain the original genotype, creating a mixed population.
E. coli is the preferred expression host for many therapeutic proteins including insulin and growth factors due to its rapid growth, well-characterized genetics, and established fermentation technology.
Substantial equivalence is a regulatory concept suggesting that if a GM crop is compositionally and nutritionally similar to its conventional counterpart, it can be considered equally safe.
Viruses have naturally evolved sophisticated mechanisms to infiltrate cells and deliver their genetic material, making modified viral vectors efficient delivery systems for therapeutic genes.
Most first-generation gene therapy approaches target somatic cells to avoid heritable genetic modifications and ethical concerns associated with germline therapy.
Homologous recombination uses regions of DNA sequence similarity (homologous arms) flanking the insert to direct accurate integration at specific chromosomal locations.
